Description

2-Methyl-6-Indolizinecarboxylic Acid Ethyl Ester is a high-purity organic building block and heterocyclic intermediate of significant interest in advanced chemical synthesis. This compound is valued for its indolizine core, a privileged scaffold in medicinal chemistry and materials science. It is primarily sought after by research institutions and industrial R&D departments engaged in the development of novel pharmaceuticals, agrochemicals, and functional organic materials.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and infectious diseases.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the biological activity of the indolizine moiety.
• Organic Electronic Materials: Acts as a building block for π-conjugated systems in the research of organic light-emitting diodes (OLEDs) and organic photovoltaics (OPVs).
• Ligand Synthesis: Employed in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Dye and Pigment Chemistry: Utilized as an intermediate for synthesizing novel heterocyclic dyes and functional colorants.
• Academic & Contract Research: A valuable reagent for methodological studies in organic synthesis and heterocyclic chemistry at universities and CROs (Contract Research Organizations).

Basic Information

Product Name	2-Methyl-6-Indolizinecarboxylic Acid Ethyl Ester
CAS No.	22320-28-1
Molecular Formula	C12H13NO2
Molecular Weight	203.24 g/mol
Synonyms	Ethyl 2-Methyl-6-indolizinecarboxylate; 2-Methylindolizine-6-carboxylic Acid Ethyl Ester; 6-(Ethoxycarbonyl)-2-methylindolizine; 2-Methyl-1-azaindene-6-carboxylic Acid Ethyl Ester; 1-Azaindene-6-carboxylic Acid, 2-methyl-, Ethyl Ester; Ethyl 2-Methyl-1-azaindene-6-carboxylate
EINECS	Contact for details

Quality Control

Our 2-Methyl-6-Indolizinecarboxylic Acid Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.