Description

1-Bromo-3-Iodopropane is a versatile bifunctional alkyl halide building block, essential for organic synthesis and advanced material development. Its dual reactive sites make it a critical intermediate for constructing complex molecular architectures through nucleophilic substitution and cross-coupling reactions. This compound is particularly valuable for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce functionalized propyl linkers.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing active pharmaceutical ingredients (APIs) and drug candidates, particularly those requiring a functionalized three-carbon chain.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and plant growth regulators that incorporate halogenated propyl groups.
• Ligand & Catalyst Preparation: Serves as a precursor for synthesizing phosphine ligands and organometallic catalysts used in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck).
• Material Science: Employed in the surface modification of polymers and nanoparticles, and in the synthesis of liquid crystals and organic semiconductors.
• Organic Synthesis Reagent: A versatile reagent for alkylation reactions, cyclopropanation, and the introduction of iodine/bromine handles for further functionalization in complex molecule construction.
• Bioconjugation & Probe Development: Useful for labeling biomolecules and synthesizing fluorescent or radioactive probes for diagnostic and research applications.

Basic Information

Product Name	1-Bromo-3-Iodopropane
CAS No.	22306-36-1
Molecular Formula	C3H6BrI
Molecular Weight	248.89 g/mol
Synonyms	3-Bromo-1-iodopropane; 3-Iodopropyl bromide; 1-Iodo-3-bromopropane; Iodobromopropane; Propane, 1-bromo-3-iodo-; Br(CH2)3I; ω-Bromo-ω'-iodopropane
EINECS	244-889-5

Quality Control

Our 1-Bromo-3-Iodopropane is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications. We support cGMP and ISO 9001 standards for reliable supply to regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong acids, bases, and oxidizing agents. Due to its light-sensitive nature and reactivity, it is recommended to store under an inert atmosphere for long-term stability.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Density (at 20°C)	2.20 - 2.30 g/mL
Refractive Index (n20D)	1.620 - 1.630
Related Substances (GC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.