Description

(7R,8S)-7,8-Diiodobicyclo[4.2.0]octa-1,3,5-triene CAS NO 22267-94-3 is a highly functionalized, stereochemically defined bicyclic organic compound featuring two iodine atoms on a strained ring system. This unique structure makes it a valuable and versatile advanced synthetic intermediate for constructing complex molecular architectures. It is primarily sought by pharmaceutical research and fine chemical synthesis laboratories for the development of novel active ingredients and specialty materials.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of complex drug candidates, particularly those requiring stereochemical precision and halogenated motifs.
• Organic Synthesis Reagent: Utilized in cross-coupling reactions (e.g., Suzuki, Stille) where the iodine atoms act as excellent leaving groups for carbon-carbon bond formation.
• Ligand and Catalyst Precursor: Used to develop novel organometallic complexes and catalysts for asymmetric synthesis.
• Material Science Research: Investigated as a monomer or precursor for creating specialized polymers with unique electronic or structural properties.
• Agrochemical Intermediate: Employed in the research and development of new crop protection agents with enhanced efficacy.
• Academic and R&D: A critical compound for methodological studies in organic chemistry, including cycloaddition reactions and strain-release functionalization.

Basic Information

Item	Details
Product Name	(7R,8S)-7,8-Diiodobicyclo[4.2.0]octa-1,3,5-triene
CAS No.	22267-94-3
Molecular Formula	C8H8I2
Molecular Weight	357.96 g/mol
Synonyms	(7R,8S)-7,8-Diiodobicyclo[4.2.0]octa-1,3,5-triene; 7,8-Diiodobicyclo[4.2.0]octa-1,3,5-triene; (1R,6S)-1,6-Diiodobicyclo[4.2.0]octa-2,4,7-triene; Bicyclo[4.2.0]octa-1,3,5-triene, 7,8-diiodo-, (7R,8S)-; 22267-94-3
EINECS	Contact for details

Quality Control

Every batch of our (7R,8S)-7,8-Diiodobicyclo[4.2.0]octa-1,3,5-triene is produced and handled under strict quality management protocols. We provide comprehensive analytical data to ensure identity, purity, and stereochemical integrity for your critical research and development projects. A detailed Certificate of Analysis (COA) including HPLC purity, chiral purity, and spectroscopic confirmation is available for each lot upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Recommended storage temperature is 2-8°C for long-term stability. Allow the container to reach room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% de
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.