Description

8-Amino-1,3,4,5-tetrahydrobenzo[b]azepine-2-one is a versatile heterocyclic organic compound featuring a benzazepine core structure, which is of significant interest in advanced chemical synthesis. This molecule serves as a critical pharmacophore and key synthetic intermediate for the development of novel active pharmaceutical ingredients (APIs). It is primarily utilized by research institutions and pharmaceutical companies engaged in the discovery and production of central nervous system (CNS) agents and other therapeutic compounds.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates, particularly those targeting neurological pathways.
• Organic Synthesis Reagent: Used in research laboratories for constructing benzazepine-based heterocyclic frameworks and exploring novel chemical spaces.
• Chemical Reference Standard: Serves as a high-purity standard for analytical method development and quality control in API manufacturing.
• Life Science Research: Employed in biochemical and pharmacological studies to investigate receptor binding and enzyme inhibition.
• Material Science Precursor: Investigated for the development of specialty chemicals and advanced organic materials.

Basic Information

Product Name	8-Amino-1,3,4,5-tetrahydrobenzo[b]azepine-2-one
CAS No.	22246-76-0
Molecular Formula	C10H12N2O
Molecular Weight	176.22 g/mol
Synonyms	8-Amino-2,3,4,5-tetrahydro-1H-benzo[b]azepin-2-one; 8-Amino-2,3,4,5-tetrahydro-1H-2-benzazepin-1-one; 8-Amino-1,3,4,5-tetrahydro-2H-1-benzazepin-2-one; 2H-1-Benzazepin-2-one, 8-amino-1,3,4,5-tetrahydro-; 8-Amino-1,3,4,5-tetrahydro-2H-benzo[b]azepin-2-one; 8-Aminotetrahydrobenzoazepinone
EINECS	Contact for details

Quality Control

Our 8-Amino-1,3,4,5-tetrahydrobenzo[b]azepine-2-one is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.