Description

6-Chloro-3,4-Dihydro-2H-Isoquinolin-1-One is a versatile and high-value heterocyclic building block, primarily utilized in advanced organic synthesis. Its core value lies in its role as a key intermediate for constructing complex molecules, particularly in the pharmaceutical and agrochemical sectors. This compound is essential for researchers and manufacturers developing active pharmaceutical ingredients (APIs), agrochemicals, and other fine chemicals, where its specific chlorinated isoquinolinone scaffold enables the creation of novel compounds with targeted biological activity.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-cancer agents, and other therapeutic small molecules.
• Agrochemical Research: Used in the development and production of advanced pesticides, herbicides, and fungicides, where its heterocyclic structure contributes to biological activity.
• Organic Synthesis & Chemical Research: Serves as a versatile precursor for synthesizing more complex heterocyclic compounds, ligands for catalysis, and other specialty chemicals in academic and industrial R&D settings.
• Material Science Precursor: Potential use in the synthesis of organic electronic materials, dyes, and photoactive compounds due to its conjugated system.

Basic Information

Product Name	6-Chloro-3,4-Dihydro-2H-Isoquinolin-1-One
CAS No.	22246-02-2
Molecular Formula	C9H8ClNO
Molecular Weight	181.62 g/mol
Synonyms	6-Chloro-1,2,3,4-tetrahydroisoquinolin-1-one; 6-Chloro-3,4-dihydro-1(2H)-isoquinolinone; 6-Chloro-1-oxo-1,2,3,4-tetrahydroisoquinoline; 6-Chloro-1-isoquinolinone, 3,4-dihydro-; 6-Chloro-3,4-dihydro-2H-isoquinolin-1-one; 22246-02-2; 6-Chloro-1,2,3,4-tetrahydroisoquinoline-1-one
EINECS	Contact for details

Quality Control

Our 6-Chloro-3,4-Dihydro-2H-Isoquinolin-1-One is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality systems are designed to meet the stringent requirements of pharmaceutical and fine chemical applications, ensuring reliable supply and traceability for our global partners.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.