Description

3-Amino-4-Methylphenylboronic Acid Hydrochloride is a high-purity, functionalized boronic acid derivative essential for modern synthetic chemistry. This compound serves as a critical building block in cross-coupling reactions, enabling the efficient construction of complex molecular architectures. It is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors for developing novel active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, including kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, leveraging its boronic acid functionality for creating diverse bioactive compounds.
• Material Science: Serves as a monomer or functionalization agent in the production of organic electronic materials, such as OLEDs and conductive polymers.
• Chemical Biology & Proteomics: Employed in the development of chemical probes and affinity ligands for studying protein interactions and enzyme activity.
• Catalyst & Ligand Development: Acts as a starting material for synthesizing specialized ligands used in homogeneous catalysis.
• Academic & Contract Research: A vital reagent for methodological development and discovery chemistry in university laboratories and CROs (Contract Research Organizations).

Basic Information

Product Name	3-Amino-4-Methylphenylboronic Acid Hydrochloride
CAS No.	22237-12-3
Molecular Formula	C7H11BClNO2
Molecular Weight	187.43 g/mol
Synonyms	(3-Amino-4-methylphenyl)boronic acid hydrochloride; 3-Amino-p-tolylboronic acid HCl; 4-Methyl-3-aminophenylboronic acid hydrochloride; Boronic acid, B-(3-amino-4-methylphenyl)-, hydrochloride; 3-Amino-4-methylbenzeneboronic acid hydrochloride; 22237-12-3; (3-Amino-4-methylphenyl)boronic acid HCl salt
EINECS	Contact for details

Quality Control

Our 3-Amino-4-Methylphenylboronic Acid Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept sealed in a dry environment to prevent moisture absorption, which can affect product stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Assay	≥ 95.0% (as hydrochloride)
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.