Description

1-Acetyl-5-Bromoindoline is a versatile and high-purity brominated indoline derivative, serving as a critical synthetic intermediate in advanced organic chemistry. Its value lies in providing a reactive scaffold for constructing complex heterocyclic compounds, enabling precise molecular modifications. This product is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries, where it is used to develop new active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and oncology targets.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators.
• Material Science: Serves as a precursor for organic light-emitting diodes (OLEDs) and other advanced electronic materials.
• Chemical Synthesis: A versatile reagent for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) to create complex biaryl structures.
• Academic & R&D: Fundamental research tool in medicinal chemistry and organic methodology development.
• Dye & Pigment Industry: Intermediate for synthesizing specialized dyes and functional colorants.

Basic Information

Product Name	1-Acetyl-5-Bromoindoline
CAS No.	22190-38-1
Molecular Formula	C10H10BrNO
Molecular Weight	240.10 g/mol
Synonyms	5-Bromo-1-acetylindoline; 1-(5-Bromo-2,3-dihydro-1H-indol-1-yl)ethanone; N-Acetyl-5-bromoindoline; 5-Bromo-N-acetylindoline; 5-Bromo-1H-indole, 2,3-dihydro-1-acetyl-; Ethanone, 1-(5-bromo-2,3-dihydro-1H-indol-1-yl)-; 22190-38-1
EINECS	Contact for details

Quality Control

Our 1-Acetyl-5-Bromoindoline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistent performance. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specification parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most critical synthesis steps.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.