Description

2-Amino-1,2,3,4-Tetrahydroisoquinoline-1,3-Dione is a specialized heterocyclic organic compound featuring a fused isoquinoline-dione structure with an amino substituent. This unique molecular architecture makes it a valuable pharmacophore and versatile synthetic building block for medicinal chemistry research and fine chemical synthesis. It is primarily sought by pharmaceutical R&D teams and advanced chemical manufacturers developing novel therapeutic agents and high-value intermediates.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of potential drug candidates, particularly those targeting neurological and cardiovascular disorders.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Organic Synthesis Building Block: Employed in the construction of complex polycyclic compounds and heterocyclic systems due to its reactive amino and carbonyl groups.
• Agrochemical Development: Investigated as an intermediate for creating novel active ingredients with potential pesticidal or herbicidal activity.
• Biochemical Probe Synthesis: Utilized in the development of molecular probes and enzyme inhibitors for biochemical and pharmacological research.

Basic Information

Product Name	2-Amino-1,2,3,4-Tetrahydroisoquinoline-1,3-Dione
CAS No.	22177-46-4
Molecular Formula	C9H8N2O2
Molecular Weight	176.18 g/mol
Synonyms	2-Aminoisoindoline-1,3-dione; 2-Amino-1,3-dioxoisoindoline; 2-Aminophthalimide; 2-Amino-1H-isoindole-1,3(2H)-dione; 2-Amino-2,3-dihydro-1H-isoindole-1,3-dione; 2-Amino-1,3-dihydro-2H-isoindole-1,3-dione; 2-Aminoisoindoline-1,3-dione; 2-Amino-1,3-isoindolinedione
EINECS	Contact for details

Quality Control

Our 2-Amino-1,2,3,4-Tetrahydroisoquinoline-1,3-Dione is produced under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical parameters are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). This compound may be moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.