Description

[S,(+)]-2-Chlorobutane CAS NO 22156-91-8 is a high-purity chiral building block, specifically the (S)-(+)-enantiomer of 2-chlorobutane. This compound is valued for its role in asymmetric synthesis, where its defined stereochemistry is crucial for inducing chirality in target molecules. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for the synthesis of enantiomerically pure intermediates and active ingredients.

Application

• Asymmetric Synthesis: A key chiral alkylating agent or electrophile in stereoselective carbon-carbon bond formation.
• Pharmaceutical Intermediates: Used in the research and development of enantiomerically pure active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Serves as a chiral precursor for the production of herbicides, fungicides, and insecticides with specific stereochemical activity.
• Ligand and Catalyst Development: Employed in the preparation of chiral ligands for transition metal catalysis.
• Material Science Research: A monomer or modifier for creating polymers with chiral centers for specialized optical or mechanical properties.
• Academic & Industrial R&D: A standard reagent for methodological studies in organic chemistry and stereochemistry.

Basic Information

Product Name	[S,(+)]-2-Chlorobutane
CAS No.	22156-91-8
Molecular Formula	C4H9Cl
Molecular Weight	92.57 g/mol
Synonyms	(S)-2-Chlorobutane; (+)-sec-Butyl chloride; (S)-(+)-sec-Butyl chloride; (S)-1-Methylpropyl chloride; (S)-2-Butyl chloride; (S)-(+)-2-Chlorobutane; sec-Butyl chloride (S-enantiomer); (2S)-2-Chlorobutane
EINECS	Contact for details

Quality Control

Our [S,(+)]-2-Chlorobutane is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by GC or HPLC, to ensure high enantiomeric excess (e.e.) and chemical purity. Certificates of Analysis (COA) detailing identity, purity, and specific test results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated place away from heat and ignition sources. Due to its highly volatile nature, keep container tightly sealed when not in use. Recommended storage temperature: 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	Clear, colorless liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 98.0%
Enantiomeric Excess (Chiral GC/HPLC)	≥ 99.0% e.e.
Specific Rotation [α]D20	Contact for details
Water Content (KF)	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.