Description

(R)-(+)-1-Phenyl-1-Butanol is a high-value chiral alcohol and a versatile building block in organic synthesis. This compound matters as a key chiral intermediate for the production of pharmaceuticals, agrochemicals, and advanced materials, where its specific stereochemistry is critical for biological activity and material properties. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, fine chemical, and fragrance industries for asymmetric synthesis and chiral resolution processes.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) drugs and anti-inflammatory agents.
• Asymmetric Catalyst Ligand Precursor: Used to synthesize chiral ligands for transition metal catalysts employed in enantioselective hydrogenation and cross-coupling reactions.
• Agrochemical Synthesis: Serves as a building block for creating chiral pesticides and herbicides with enhanced efficacy and environmental profile.
• Flavor and Fragrance Ingredient: Employed in the synthesis of specific aroma chemicals where the (R)-enantiomer imparts the desired olfactory characteristic.
• Material Science Research: Used in the development of chiral liquid crystals and polymers with unique optical and electronic properties.
• Academic and R&D Laboratories: A standard reagent for methodological studies in organic chemistry, including studies on kinetic resolution and stereoselective reactions.

Basic Information

Product Name	(R)-(+)-1-Phenyl-1-Butanol
CAS No.	22144-60-1
Molecular Formula	C10H14O
Molecular Weight	150.22 g/mol
Synonyms	(R)-(+)-1-Phenylbutan-1-ol; (R)-1-Phenyl-1-butanol; (R)-1-Phenylbutanol; (+)-(R)-1-Phenyl-1-butanol; (R)-α-Ethylbenzyl alcohol; (R)-1-Butanol, 1-phenyl-; (R)-Phenylbutyl alcohol; (R)-Sec-butylphenylmethanol
EINECS	Contact for details

Quality Control

Our (R)-(+)-1-Phenyl-1-Butanol is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC for enantiomeric excess (ee) and standard purity assays, to ensure it meets the high standards required for synthetic applications. Certificates of Analysis (COA) with detailed specifications for identity, purity, and chiral purity are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Specific Rotation [α]D20	+40.0° to +44.0° (c=1 in CHCl3)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.