Description

3-Formyl-5-Nitro-1H-Indole-2-Carboxylic Acid Ethyl Ester is a high-purity, multi-functional indole derivative serving as a critical building block in advanced organic synthesis. Its molecular structure, featuring both formyl and nitro functional groups, makes it an exceptionally versatile intermediate for constructing complex heterocyclic systems. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to develop novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-inflammatory agents, and anticancer compounds.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators that leverage the indole scaffold's biological activity.
• Organic Synthesis Building Block: Employed in complex multi-step syntheses, including palladium-catalyzed cross-coupling reactions and the construction of fused polycyclic heteroaromatic systems.
• Material Science Research: Investigated as a monomer or functional component in the development of specialty polymers and organic electronic materials.
• Dye and Pigment Synthesis: Serves as an intermediate for creating specialized indole-based colorants and fluorescent markers.

Basic Information

Product Name	3-Formyl-5-Nitro-1H-Indole-2-Carboxylic Acid Ethyl Ester
CAS No.	22120-89-4
Molecular Formula	C₁₂H₁₀N₂O₅
Molecular Weight	262.22 g/mol
Synonyms	Ethyl 3-Formyl-5-nitro-1H-indole-2-carboxylate; 5-Nitro-1H-indole-2-carboxylic acid, 3-formyl-, ethyl ester; Ethyl 5-nitro-3-formylindole-2-carboxylate; 3-Formyl-5-nitroindole-2-carboxylic acid ethyl ester; 2-Carbethoxy-3-formyl-5-nitroindole; 1H-Indole-2-carboxylic acid, 3-formyl-5-nitro-, ethyl ester
EINECS	Contact for details

Quality Control

Our 3-Formyl-5-Nitro-1H-Indole-2-Carboxylic Acid Ethyl Ester is manufactured under strict quality management protocols. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its light-sensitive nature and propensity for oxidation, it is recommended to handle under an inert atmosphere for long-term storage and to minimize exposure to air and moisture.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.