Description

4-Hydroxyisoquinoline-3-Carboxylic Acid is a versatile heterocyclic carboxylic acid derivative that serves as a critical building block in advanced organic synthesis. Its unique fused-ring structure makes it a valuable precursor for the development of complex molecules with specific biological and chemical properties. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in medicinal chemistry, particularly for the synthesis of novel drug candidates and fine chemicals.

Application

• Pharmaceutical Intermediate: A key starting material or synthon in the multi-step synthesis of potential therapeutic agents, including kinase inhibitors and other bioactive molecules.
• Medicinal Chemistry Research: Used extensively in research and development for structure-activity relationship (SAR) studies and the creation of compound libraries for high-throughput screening.
• Fine Chemical Synthesis: Employed as a specialized building block for constructing complex heterocyclic frameworks found in agrochemicals, dyes, and functional materials.
• Ligand and Chelating Agent Precursor: Its structure allows for modification into chelating ligands used in catalysis or metal complexation studies.
• Academic and R&D Laboratories: Serves as a standard or experimental compound in university and industrial research projects exploring new organic reactions and methodologies.

Basic Information

Product Name	4-Hydroxyisoquinoline-3-Carboxylic Acid
CAS No.	22080-18-8
Molecular Formula	C₁₀H₇NO₃
Molecular Weight	189.17 g/mol
Synonyms	4-Hydroxy-3-isoquinolinecarboxylic Acid; 3-Carboxy-4-hydroxyisoquinoline; 4-Hydroxyisoquinoline-3-carboxylic acid; Isoquinoline-3-carboxylic acid, 4-hydroxy-; 4-Hydroxy-1-azanaphthalene-3-carboxylic acid
EINECS	Contact for details

Quality Control

Our 4-Hydroxyisoquinoline-3-Carboxylic Acid is produced and tested under a strict quality management system to ensure batch-to-batch consistency and high purity for research and development applications. We provide comprehensive analytical data with each shipment. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request and are standard for all commercial orders.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area. Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere or with appropriate desiccants to prevent degradation. Recommended long-term storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.