Description

(-)-Diisopinocampheyl Borane is a highly versatile and enantiomerically pure organoborane reagent, widely recognized for its exceptional stereoselectivity in organic synthesis. Its core value lies in enabling the precise, asymmetric synthesis of chiral molecules, a critical requirement for developing pharmaceuticals and fine chemicals. This product is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries who require reliable, high-purity chiral auxiliaries and reducing agents.

Application

• Asymmetric Hydroboration: Key reagent for the enantioselective hydroboration of prochiral alkenes to produce chiral organoboranes.
• Chiral Alcohol Synthesis: Crucial for the stereocontrolled reduction of prochiral ketones to yield enantiomerically enriched secondary alcohols.
• Pharmaceutical Intermediate Production: Used in the synthesis of chiral active pharmaceutical ingredients (APIs) and complex natural products.
• Agrochemical Research: Employed in creating enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Fine Chemical and Fragrance Synthesis: Facilitates the production of chiral flavor and fragrance compounds with high optical purity.
• Material Science: Applied in the development of chiral polymers and ligands for asymmetric catalysis.

Basic Information

Product Name	(-)-Diisopinocampheyl Borane
CAS No.	21932-54-7
Molecular Formula	C20H35B
Molecular Weight	286.30 g/mol
Synonyms	(-)-DIP-Chloride™; (1R)-(-)-Diisopinocampheylborane; (1R)-(-)-B-Chlorodiisopinocampheylborane; (1R)-(-)-Bis(pinanyl)borane; Ipc2BH; DIP-Chloride; (1R,2S,5R)-(-)-Diisopinocampheylborane; Alpine Borane® (related reagent)
EINECS	Contact for details

Quality Control

Our (-)-Diisopinocampheyl Borane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity assay and impurity profiling, to ensure it meets the high standards required for asymmetric synthesis. Certificates of Analysis (COA) with detailed chromatographic data (HPLC, GC) and optical rotation values are provided to guarantee reproducible performance and lot-to-lot consistency for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) at 2-8°C in a cool, dry place. This material is hygroscopic (moisture-sensitive) and easily oxidized; containers must be kept sealed and handled under anhydrous conditions to maintain purity and reactivity.

Specification

Item	Specification
Appearance	White to off-white crystalline solid or solution
Identification (IR)	Conforms to structure
Assay (Titration)	≥ 95.0%
Chiral Purity (Enantiomeric Excess)	≥ 98.0% ee
Optical Rotation [α]D	Contact for details
Solvent (if supplied as solution)	Specified (e.g., Tetrahydrofuran, Hexanes)
Water Content (Karl Fischer)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.