Description

7,8-Dihydroisoquinolin-5(6H)-One is a versatile heterocyclic building block and key synthetic intermediate in organic chemistry. Its unique fused-ring structure makes it a valuable scaffold for constructing complex molecules in pharmaceutical and agrochemical research. This compound is primarily sought after by R&D chemists and process development scientists working in medicinal chemistry, particularly for the synthesis of novel active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of potential drug candidates, especially those targeting neurological and cardiovascular diseases.
• Medicinal Chemistry Research: Serves as a core scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Agrochemical Development: Used in the research and synthesis of novel herbicides, fungicides, and plant growth regulators.
• Fine Chemical Synthesis: Employed as a building block for creating complex dyes, pigments, and specialty chemicals.
• Academic & Institutional R&D: Utilized in universities and research institutes for methodological studies in heterocyclic and synthetic organic chemistry.
• Material Science Precursor: Investigated for the development of organic electronic materials and ligands for catalytic systems.

Basic Information

Product Name	7,8-Dihydroisoquinolin-5(6H)-One
CAS No.	21917-86-2
Molecular Formula	C9H9NO
Molecular Weight	147.17 g/mol
Synonyms	5,6,7,8-Tetrahydroisoquinolin-5-one; 5,6,7,8-Tetrahydro-5-isoquinolinone; 7,8-Dihydro-5(6H)-isoquinolinone; 5-Oxo-5,6,7,8-tetrahydroisoquinoline; Isoquinoline, 5,6,7,8-tetrahydro-5-oxo-; 5(6H)-Isoquinolinone, 7,8-dihydro-; 5,6,7,8-Tetrahydroisoquinoline-5-one
EINECS	Contact for details

Quality Control

We maintain stringent quality control protocols for all our fine chemical intermediates. Each batch of 7,8-Dihydroisoquinolin-5(6H)-One is analyzed using advanced techniques including HPLC, GC, NMR, and mass spectrometry to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment. Our quality system is designed to support cGMP and ISO standards for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.