Description

1H-2,3-Benzothiazin-4(3H)-One 2,2-Dioxide is a high-purity organic chemical building block and key intermediate of significant interest in advanced pharmaceutical and agrochemical synthesis. Its value lies in its role as a versatile precursor for developing novel active ingredients, particularly in the research and development of new therapeutic agents and crop protection products. This compound is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to innovate and scale new molecular entities.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and anti-inflammatory targets.
• Agrochemical Synthesis: Used as a key precursor in the research and development of new herbicides, fungicides, and insecticides.
• Organic Synthesis & Research: Serves as a versatile scaffold for heterocyclic chemistry and the development of new chemical entities in academic and industrial R&D laboratories.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, dyes, and advanced materials requiring the benzothiazine dioxide core structure.

Basic Information

Product Name	1H-2,3-Benzothiazin-4(3H)-One 2,2-Dioxide
CAS No.	21784-53-2
Molecular Formula	C8H5NO3S
Molecular Weight	195.20 g/mol
Synonyms	2,1-Benzothiazin-4(3H)-one 2,2-dioxide; 3,4-Dihydro-2,1-benzothiazin-4-one 2,2-dioxide; 1,2-Benzothiazin-4(3H)-one 2,2-dioxide; 2,2-Dioxo-2,1-benzothiazin-4(3H)-one; 4-Oxo-3,4-dihydro-2,1-benzothiazine-2,2-dioxide; Saccharin intermediate; Benzothiazine dioxide
EINECS	244-581-8

Quality Control

Our 1H-2,3-Benzothiazin-4(3H)-One 2,2-Dioxide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets exacting standards for research and production use. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.