Description

Succinic Acid-D6 is a stable isotope-labeled analog of succinic acid, where six hydrogen atoms are replaced by deuterium. This high-purity compound is essential for applications requiring precise internal standards and metabolic pathway tracing. It is a critical reagent for researchers and manufacturers in the pharmaceutical, biotechnology, and analytical chemistry sectors.

Application

• Quantitative Mass Spectrometry (MS): Serves as a reliable internal standard for the accurate quantification of endogenous succinic acid in complex biological matrices like plasma, urine, and tissue extracts.
• Metabolic Flux Analysis (MFA): Used in 13C and deuterium tracer studies to elucidate the activity of metabolic pathways, such as the TCA cycle, in cell cultures and in vivo models.
• NMR Spectroscopy: Acts as a deuterated standard or reference compound in nuclear magnetic resonance experiments, aiding in method development and signal calibration.
• Pharmaceutical R&D: Employed in drug metabolism and pharmacokinetics (DMPK) studies to track the fate of drug molecules and their metabolites.
• Diagnostic Kit Manufacturing: Integrated into high-precision clinical diagnostic assays and kits for metabolic disorder screening.
• Biochemical Research: A key tool for studying enzyme kinetics, isotopic dilution, and metabolic engineering in academic and industrial laboratories.

Basic Information

Product Name	Succinic Acid-D6
CAS No.	21668-90-6
Molecular Formula	C4D6O4
Molecular Weight	124.12 g/mol
Synonyms	Butanedioic Acid-d6; Deuterated Succinic Acid; Succinic-d6 Acid; (2,2,3,3-D4)-1,4-Butanedioic Acid; 1,4-Butanedioic-2,2,3,3-d4 Acid; 1,2-Ethanedicarboxylic Acid-d6; Amber Acid-d6
EINECS	Contact for details

Quality Control

Every batch of our Succinic Acid-D6 is produced and analyzed under strict quality management protocols to ensure exceptional isotopic purity and chemical integrity. We provide comprehensive Certificates of Analysis (COA) detailing isotopic enrichment (D-atom %), chemical purity, and specific analytical results. Our quality systems support compliance with cGMP and ISO standards for research and manufacturing use.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. The product is hygroscopic (moisture-sensitive); ensure containers are sealed after each use to prevent absorption of atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Isotopic Purity (D-atom %)	≥ 98% (by 1H-NMR or MS)
Chemical Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5% w/w
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.