Description

6,7-Dimethoxy-1-Chloroisoquinoline is a versatile halogenated isoquinoline derivative that serves as a critical synthetic intermediate in advanced organic chemistry. Its unique structure, featuring both chloro and dimethoxy substituents, makes it a valuable building block for constructing complex molecules with tailored properties. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, particularly in the development of kinase inhibitors, alkaloid analogs, and other bioactive heterocycles.
• Agrochemical Research: Used as a building block for creating novel herbicides, fungicides, and plant growth regulators with specific modes of action.
• Material Science: Serves as a monomer or functional unit in the development of advanced organic electronic materials, such as charge-transport layers or luminescent compounds.
• Chemical Synthesis: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic substitution reactions to introduce the isoquinoline scaffold into more complex molecular architectures.
• Academic & R&D: A valuable reagent for methodological studies in organic synthesis and for exploring new chemical space in medicinal chemistry programs.

Basic Information

Product Name	6,7-Dimethoxy-1-Chloroisoquinoline
CAS No.	21560-29-2
Molecular Formula	C₁₁H₁₀ClNO₂
Molecular Weight	223.66 g/mol
Synonyms	1-Chloro-6,7-dimethoxyisoquinoline; 6,7-Dimethoxy-1-chloroisoquinoline; 1-Chloro-6,7-dimethoxy-isoquinoline; Isoquinoline, 1-chloro-6,7-dimethoxy-; 21560-29-2; 6,7-Dimethoxy-1-chloro-isoquinoline
EINECS	Contact for details

Quality Control

Our 6,7-Dimethoxy-1-Chloroisoquinoline is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing key parameters such as identity, purity, and impurity profile. We support cGMP compliance for advanced applications and can provide material tailored to specific research or development project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.