Description

5-Cyano-2-Thiophene Carbaldehyde is a versatile heterocyclic building block featuring both an aldehyde and a nitrile functional group on a thiophene core, enabling diverse chemical transformations. This compound is essential for the synthesis of complex organic molecules, particularly in the development of advanced materials and active pharmaceutical ingredients. It is a critical intermediate for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries seeking to develop novel thiophene-based compounds.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for drugs targeting central nervous system disorders and anti-infectives.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides that leverage the thiophene scaffold for enhanced activity.
• Material Science & Organic Electronics: Serves as a building block for conjugated polymers and small molecules used in organic light-emitting diodes (OLEDs), organic photovoltaics (OPVs), and field-effect transistors (OFETs).
• Ligand & Catalyst Development: The aldehyde and nitrile groups allow for the creation of novel chelating ligands for transition metal catalysts used in cross-coupling reactions.
• Dye & Pigment Chemistry: Acts as a starting material for the synthesis of specialized dyes and pigments with specific light-absorption properties.
• Research & Development: A valuable tool for medicinal chemistry and chemical biology research in exploring new heterocyclic compound libraries.

Basic Information

Product Name	5-Cyano-2-Thiophene Carbaldehyde
CAS No.	21512-16-3
Molecular Formula	C6H3NOS
Molecular Weight	137.16 g/mol
Synonyms	2-Formyl-5-cyanothiophene; 5-Cyano-2-thiophenecarboxaldehyde; 2-Thiophenecarboxaldehyde, 5-cyano-; 5-Cyanothiophene-2-carbaldehyde; Thiophene-2-carbaldehyde, 5-cyano-; 5-Cyano-2-thienylcarboxaldehyde; 2-Cyano-5-formylthiophene
EINECS	Contact for details

Quality Control

Our 5-Cyano-2-Thiophene Carbaldehyde is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is easily oxidized and should be handled under an inert atmosphere for long-term storage. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.