Description

1-Aza-Bicyclo[2.2.1]Heptan-3-One is a versatile bicyclic lactam compound, also known as 3-Quinuclidinone, serving as a critical synthetic intermediate in advanced organic chemistry. Its rigid, bridged structure makes it a valuable building block for constructing complex molecules with specific three-dimensional configurations. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical sectors developing novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for neurological and muscarinic receptor-targeting drugs.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, leveraging its nitrogen-containing bicyclic framework.
• Chemical Research & Development: A fundamental scaffold in medicinal chemistry for creating novel compound libraries and exploring structure-activity relationships (SAR).
• Ligand and Catalyst Preparation: Serves as a starting material for synthesizing chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Precursor: Potential monomer or modifier in the synthesis of specialized polymers with unique thermal or mechanical properties.

Basic Information

Product Name	1-Aza-Bicyclo[2.2.1]Heptan-3-One
CAS No.	21472-89-9
Molecular Formula	C6H9NO
Molecular Weight	111.14 g/mol
Synonyms	3-Quinuclidinone; 1-Azabicyclo[2.2.1]heptan-3-one; NSC 403169; Quinuclidin-3-one; Bicyclo[2.2.1]heptan-3-one, 1-aza-; 3-Oxo-1-azabicyclo[2.2.1]heptane
EINECS	244-415-6

Quality Control

Our 1-Aza-Bicyclo[2.2.1]Heptan-3-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee batch-to-batch consistency and support your regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.