Description

n-[2-(5-Methoxy-1H-Indole-3-Yl)Ethyl]-2-Chloroacetamide is a specialized indole derivative with a chloroacetamide functional group, serving as a critical synthetic intermediate in advanced organic synthesis. Its molecular architecture makes it a valuable precursor for constructing complex pharmacophores, particularly in medicinal chemistry research and development. This compound is primarily sought by fine chemical manufacturers and R&D laboratories focused on developing novel bioactive molecules, including potential pharmaceuticals and agrochemicals.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel therapeutic agents, particularly those targeting neurological and psychiatric pathways.
• Medicinal Chemistry Research: Used as a core scaffold or precursor for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Agrochemical Development: Serves as an intermediate in the research and synthesis of new crop protection agents and plant growth regulators.
• Biochemical Probe Synthesis: Utilized for creating labeled compounds or probes for studying biological systems and enzyme mechanisms.
• Fine Chemical Synthesis: Employed in multi-step organic syntheses to introduce specific indole and amide functionalities into target molecules.

Basic Information

Product Name	n-[2-(5-Methoxy-1H-Indole-3-Yl)Ethyl]-2-Chloroacetamide
CAS No.	21424-91-9
Molecular Formula	C₁₃H₁₅ClN₂O₂
Molecular Weight	266.72 g/mol
Synonyms	2-Chloro-N-[2-(5-methoxy-1H-indol-3-yl)ethyl]acetamide; 5-Methoxytryptamine Chloroacetamide; N-(2-(5-Methoxy-1H-indol-3-yl)ethyl)-2-chloroacetamide; 2-Chloro-N-(2-(5-methoxy-1H-indol-3-yl)ethyl)acetamide; 5-Methoxy-3-(2-chloroacetamidoethyl)indole; 21424-91-9; 5-Methoxytryptamine, N-chloroacetyl-; Chloroacetamide derivative of 5-methoxytryptamine
EINECS	Contact for details

Quality Control

Our n-[2-(5-Methoxy-1H-Indole-3-Yl)Ethyl]-2-Chloroacetamide is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and synthesis. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as identity, purity, and impurity profiles. Our quality system is designed to meet the stringent requirements of GMP and ISO standards for fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and handling properties. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.