Description

1-Bromo-2-Phenylethynyl-Benzene is a high-purity organic building block featuring a bromine-substituted aromatic core linked to a phenylacetylene moiety. This compound matters as a versatile and reactive intermediate, enabling precise molecular construction in advanced synthetic chemistry. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries for constructing complex molecules, particularly in cross-coupling reactions and as a precursor for functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, especially those requiring diarylacetylene scaffolds.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and plant growth regulators.
• Material Science Precursor: Employed in the creation of organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors, due to its conjugated system.
• Cross-Coupling Reactions: Acts as a crucial electrophilic partner in Sonogashira, Suzuki, and other palladium-catalyzed cross-coupling reactions to form carbon-carbon bonds.
• Ligand and Catalyst Development: Utilized as a starting material for synthesizing specialized ligands and organometallic catalysts.
• Academic & Industrial Research: A valuable reagent for methodological development and exploring new synthetic pathways in organic chemistry laboratories.

Basic Information

Product Name	1-Bromo-2-Phenylethynyl-Benzene
CAS No.	21375-88-2
Molecular Formula	C₁₄H₉Br
Molecular Weight	257.13 g/mol
Synonyms	2-Bromodiphenylacetylene; 1-Bromo-2-(phenylethynyl)benzene; (2-Bromophenyl)phenylacetylene; o-Bromodiphenylacetylene; 2-Bromo-1,1'-biphenyl-2'-yne; 2-Bromobiphenyl-2'-acetylene; Bromo(phenylethynyl)benzene; 2-Bromodiphenylethyne
EINECS	Contact for details

Quality Control

Our 1-Bromo-2-Phenylethynyl-Benzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee compliance with your research and process requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flames. This compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.