Description

Bis(Dimethylsilyl)Acetamide is a versatile organosilicon reagent primarily used as a powerful silylating agent and a precursor in advanced chemical synthesis. Its core value lies in its ability to efficiently introduce dimethylsilyl groups, making it indispensable for protecting sensitive functional groups and modifying molecular structures. This compound is critically needed by R&D chemists and process engineers in the pharmaceutical, agrochemical, and specialty materials industries for developing active ingredients and novel silicon-based polymers.

Application

• Pharmaceutical Intermediate Synthesis: Used as a key silylating agent in the multi-step synthesis of complex drug molecules and active pharmaceutical ingredients (APIs).
• Agrochemical Production: Employed in the manufacture of advanced pesticides and herbicides where silicon incorporation enhances stability or bioavailability.
• Polymer & Material Science: Serves as a monomer or cross-linking agent in the development of silicone-based polymers, resins, and advanced composite materials.
• Organic Synthesis Reagent: Functions as a protecting group for alcohols, amines, and other nucleophiles during complex organic transformations.
• Surface Modification: Utilized to modify the surface properties of silica, glass, or other oxides to alter hydrophobicity or reactivity.
• Catalyst & Ligand Preparation: Acts as a precursor for synthesizing organosilicon ligands and catalysts used in homogeneous catalysis.

Basic Information

Product Name	Bis(Dimethylsilyl)Acetamide
CAS No.	21305-90-8
Molecular Formula	C6H17NOSi2
Molecular Weight	175.38 g/mol
Synonyms	N,N-Bis(dimethylsilyl)acetamide; Acetamide, N,N-bis(dimethylsilyl)-; BSA (in some contexts); Bis(dimethylhydrosilyl)acetamide; 1,1'-(Acetylimino)bis[1,1-dimethylsilane]; N-Acetylbis(dimethylsilyl)amine; (Dimethylsilyl)acetamide dimer
EINECS	Contact for details

Quality Control

Our Bis(Dimethylsilyl)Acetamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including assay by GC or NMR and impurity profiling, to ensure it meets the high-purity standards required for sensitive synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and specific test results is provided with every shipment to guarantee traceability and consistency for your critical processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from strong bases and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/NMR)	≥ 97.0%
Purity (by GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.