Description

2-[(4-Fluorophenyl)Amino]-1,3-Thiazol-4(5H)-One is a specialized heterocyclic organic compound featuring a thiazolone core substituted with a 4-fluorophenylamino group. This structure makes it a valuable key intermediate and building block in advanced organic synthesis, particularly for the development of novel active pharmaceutical ingredients (APIs). It is primarily sought after by pharmaceutical R&D teams and fine chemical manufacturers engaged in creating new therapeutic agents, agrochemicals, and high-performance materials.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-inflammatory agents, and antimicrobials.
• Agrochemical Research: Serves as a building block for developing new generation herbicides, fungicides, and plant growth regulators with enhanced efficacy.
• Material Science: Used in the research and development of advanced polymers, liquid crystals, and organic electronic materials due to its conjugated system.
• Chemical Synthesis: Acts as a versatile scaffold for constructing more complex heterocyclic compounds in academic and industrial research laboratories.
• Biochemical Probe Development: Utilized in medicinal chemistry for creating molecular probes to study enzyme inhibition and biological pathways.

Basic Information

Product Name	2-[(4-Fluorophenyl)Amino]-1,3-Thiazol-4(5H)-One
CAS No.	21262-73-7
Molecular Formula	C9H7FN2OS
Molecular Weight	210.23 g/mol
Synonyms	4(5H)-Thiazolone, 2-[(4-fluorophenyl)amino]-; 2-(4-Fluoroanilino)-4,5-dihydro-1,3-thiazol-4-one; 2-(4-Fluoroanilino)-1,3-thiazol-4(5H)-one; 2-[(4-Fluorophenyl)amino]-4,5-dihydro-1,3-thiazol-4-one; 2-Amino-4-(4-fluorophenyl)-1,3-thiazol-5(4H)-one (tautomeric form); 4-Fluoro-N-(4-oxo-4,5-dihydro-1,3-thiazol-2-yl)aniline
EINECS	Contact for details

Quality Control

Our 2-[(4-Fluorophenyl)Amino]-1,3-Thiazol-4(5H)-One is produced under strict quality management protocols. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and structural identity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality systems are designed to support cGMP-compliant applications in pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and handling properties. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.