Description

2-[3-(Tetrahydro-2H-Pyran-2-Yloxy)Propyl]Aminoethanethiol Sulfate is a specialized organosulfur compound featuring a protected thiol group and a sulfate moiety, making it a valuable intermediate for advanced chemical synthesis. This compound is engineered to provide controlled reactivity, which is essential for constructing complex molecular architectures in pharmaceutical and fine chemical research. It is primarily sought by R&D chemists and process development scientists working on novel drug candidates, peptide mimetics, and high-value specialty chemicals where precise functional group manipulation is required.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring thiol or disulfide linkages.
• Peptide Chemistry: Used for the introduction of protected cysteine analogs or for creating stable, branched peptide structures.
• Ligand Synthesis: Serves as a precursor for chelating agents and ligands used in catalysis and metal complexation.
• Polymer Modification: Employed to incorporate functional thiol groups into polymer backbones for cross-linking or surface functionalization.
• Bioconjugation: Useful in developing linkers for antibody-drug conjugates (ADCs) or protein labeling due to its reactive handles.
• Material Science Research: Applied in the development of novel organic-inorganic hybrid materials and self-assembled monolayers (SAMs).

Basic Information

Product Name	2-[3-(Tetrahydro-2H-Pyran-2-Yloxy)Propyl]Aminoethanethiol Sulfate
CAS No.	21220-89-3
Molecular Formula	C10H21NO5S2
Molecular Weight	299.41 g/mol
Synonyms	2-[[3-(Tetrahydro-2H-pyran-2-yloxy)propyl]amino]ethanethiol sulfate; 2-((3-(Tetrahydro-2H-pyran-2-yloxy)propyl)amino)ethane-1-thiol sulfate; Aminoethanethiol sulfate derivative with THP-protected linker; THP-O-(CH2)3-NH-(CH2)2-SH sulfate; N-[2-(Sulfato)ethyl]-3-(tetrahydro-2H-pyran-2-yloxy)-1-propanamine (alternate); THP-protected amino thiol sulfate; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Every batch of 2-[3-(Tetrahydro-2H-Pyran-2-Yloxy)Propyl]Aminoethanethiol Sulfate is manufactured under strict quality management systems. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request, detailing purity, identity, and impurity profiles to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if necessary to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.