Description

Methyl 3-Hydroxybenzo[B]Thiophene-2-Carboxylate 1,1-Dioxide is a high-purity, synthetically valuable sulfone derivative and a key heterocyclic building block. This compound matters for its role as a versatile intermediate in the synthesis of complex molecules, particularly in advanced pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, leveraging its unique sulfone and benzo[b]thiophene structure.
• Material Science Research: Serves as a precursor for developing organic electronic materials, such as novel semiconductors or light-emitting components, due to its fused aromatic system.
• Chemical Biology & Proteomics: Employed as a specialty reagent or linker in the design of chemical probes and activity-based protein profiling (ABPP) agents.
• Academic & Contract Research: Essential for methodological development in organic synthesis and heterocyclic chemistry within university and CRO (Contract Research Organization) laboratories.
• Custom Synthesis & Scale-Up: A starting material for custom manufacturing and process chemistry for clients requiring specific, high-value derivatives.

Basic Information

Product Name	Methyl 3-Hydroxybenzo[B]Thiophene-2-Carboxylate 1,1-Dioxide
CAS No.	21211-28-9
Molecular Formula	C10H8O5S
Molecular Weight	240.23 g/mol
Synonyms	Methyl 3-hydroxybenzo[b]thiophene-2-carboxylate S,S-dioxide; 3-Hydroxybenzo[b]thiophene-2-carboxylic acid methyl ester 1,1-dioxide; Benzo[b]thiophene-2-carboxylic acid, 3-hydroxy-, methyl ester, 1,1-dioxide; Methyl 3-hydroxy-1,1-dioxo-1-benzothiophene-2-carboxylate; 2-Methoxycarbonyl-3-hydroxybenzo[b]thiophene 1,1-dioxide
EINECS	Contact for details

Quality Control

Our Methyl 3-Hydroxybenzo[B]Thiophene-2-Carboxylate 1,1-Dioxide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support development and commercial projects with material that meets the stringent requirements of pharmaceutical and advanced chemical synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). The compound may be light-sensitive; prolonged exposure to light should be avoided. Keep container tightly sealed when not in use to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.