Description

3-Chlorobenzo[B]Thiophene-2-Carboxylic Acid is a high-purity, versatile heterocyclic building block essential for advanced organic synthesis. Its core value lies in its functionalized structure, which serves as a critical precursor in the development of complex molecules for pharmaceutical and material science applications. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Research: Used as a building block for developing new herbicides, fungicides, and insecticides with improved efficacy and selectivity.
• Material Science Precursor: Employed in the synthesis of organic semiconductors, conductive polymers, and liquid crystals for electronic and optoelectronic devices.
• Chemical Synthesis Reagent: Serves as a versatile starting material for further functionalization, including amide coupling, esterification, and metal-catalyzed cross-coupling reactions.
• Academic & Contract Research: Utilized in university and CRO laboratories for methodological development and exploring new chemical spaces in heterocyclic chemistry.

Basic Information

Product Name	3-Chlorobenzo[B]Thiophene-2-Carboxylic Acid
CAS No.	21211-22-3
Molecular Formula	C9H5ClO2S
Molecular Weight	212.65 g/mol
Synonyms	3-Chlorobenzo[b]thiophene-2-carboxylic acid; 3-Chloro-1-benzothiophene-2-carboxylic acid; 2-Benzothiophenecarboxylic acid, 3-chloro-; 3-Chloro-2-benzothiophenecarboxylic acid; 3-Chlorobenzo[b]thiophene-2-carboxylate; 3-Chloro-2-carboxybenzothiophene; 21211-22-3; 3-Chloro-benzo[b]thiophene-2-carboxylic acid
EINECS	Contact for details

Quality Control

Our 3-Chlorobenzo[B]Thiophene-2-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to quality assurance ensures the material meets the stringent requirements for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.