Description

5-(Aminomethyl)Thiophene-2-Sulfonamide Hydrochloride is a high-purity, functionalized heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of novel pharmaceuticals and bioactive molecules, particularly those targeting enzymatic pathways where the sulfonamide and aminomethyl motifs are critical. It is primarily needed by research and development chemists in the pharmaceutical, agrochemical, and material science industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of potential drug candidates, especially carbonic anhydrase inhibitors and other enzyme-targeted therapies.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators that leverage the thiophene-sulfonamide scaffold.
• Chemical Biology Probe Synthesis: Serves as a precursor for creating molecular probes to study biological processes and enzyme functions.
• Material Science Precursor: Can be utilized in the synthesis of functionalized polymers or organic electronic materials with specific optoelectronic properties.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific custom synthesis projects.

Basic Information

Product Name	5-(Aminomethyl)Thiophene-2-Sulfonamide Hydrochloride
CAS No.	21151-36-0
Molecular Formula	C6H9N2O2S2·HCl
Molecular Weight	248.74 g/mol
Synonyms	2-Thiophenesulfonamide, 5-(aminomethyl)-, hydrochloride; 5-(Aminomethyl)-2-thiophenesulfonamide hydrochloride; 5-(Aminomethyl)thiophene-2-sulfonamide HCl; 5-AMT hydrochloride; 5-(Aminomethyl)-2-thienylsulfonamide hydrochloride; 5-(Aminomethyl)-2-sulfamoylthiophene hydrochloride; 21151-36-0
EINECS	Contact for details

Quality Control

Our 5-(Aminomethyl)Thiophene-2-Sulfonamide Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.