Description

5-Chloro-3-Phenyl-1H-Indole-2-Carboxylic Acid is a high-purity, synthetically versatile indole derivative. This compound serves as a critical pharmaceutical intermediate and organic building block for advanced research and development. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for the synthesis of novel active compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-inflammatory pathways.
• Agrochemical Research: Used as a building block for developing new herbicides, fungicides, and plant growth regulators with enhanced efficacy.
• Material Science: Serves as a monomer or functional component in the development of advanced organic electronic materials and specialty polymers.
• Academic & Contract Research: Essential for medicinal chemistry programs, structure-activity relationship (SAR) studies, and library synthesis in academic and CRO (Contract Research Organization) settings.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of complex, high-value specialty chemicals and dyes.

Basic Information

Product Name	5-Chloro-3-Phenyl-1H-Indole-2-Carboxylic Acid
CAS No.	21139-31-1
Molecular Formula	C15H10ClNO2
Molecular Weight	271.70 g/mol
Synonyms	5-Chloro-3-phenylindole-2-carboxylic acid; 1H-Indole-2-carboxylic acid, 5-chloro-3-phenyl-; 3-Phenyl-5-chloroindole-2-carboxylic acid; 5-Chloro-3-phenyl-1H-indole-2-carboxylic acid; 2-Carboxy-5-chloro-3-phenylindole; 5-Chloro-3-phenylindol-2-carbonsäure (German); Acide 5-chloro-3-phényl-1H-indole-2-carboxylique (French)
EINECS	Contact for details

Quality Control

Our 5-Chloro-3-Phenyl-1H-Indole-2-Carboxylic Acid is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment. We support cGMP compliance for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.