Description

3-Thiophenemalonic Acid is a versatile heterocyclic dicarboxylic acid derivative that serves as a critical building block in advanced organic synthesis. Its value lies in the reactive malonic acid moiety attached to the thiophene ring, enabling it to participate in condensation and cyclization reactions to construct complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries, particularly for developing novel active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of thiophene-containing drug candidates and active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Building block for creating novel herbicides, fungicides, and insecticides with thiophene cores.
• Organic Electronic Materials: Used in the development of conjugated polymers and small molecules for organic semiconductors, OLEDs, and solar cells.
• Ligand and Catalyst Development: Serves as a starting material for synthesizing chelating ligands used in catalysis and metal-organic frameworks (MOFs).
• Chemical Research & Development: A valuable reagent for heterocyclic and medicinal chemistry research in academic and industrial laboratories.
• Dye and Pigment Intermediate: Employed in the synthesis of specialized dyes and pigments with specific optical properties.

Basic Information

Product Name	3-Thiophenemalonic Acid
CAS No.	21080-92-2
Molecular Formula	C7H6O4S
Molecular Weight	186.19 g/mol
Synonyms	3-Thienylmalonic Acid; Thiophene-3-malonic Acid; 3-Carboxythiophene-2-acetic Acid; 3-Thiophenedicarboxylic Acid, 2-Carboxymethyl-; 2-(3-Thienyl)malonic Acid; 3-Thiophene-2-acetic Acid, α-Carboxy-; 3-Thienylpropanedioic Acid
EINECS	Contact for details

Quality Control

Our 3-Thiophenemalonic Acid is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data, including HPLC purity, identity confirmation by FT-IR and NMR, and residual solvent analysis. A Certificate of Analysis (COA) detailing all specifications is supplied with each shipment. Our quality systems support compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residual Solvents (GC)	Meets ICH limits

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.