Description

Amarogentin is a highly valued secoiridoid glycoside compound, recognized for its intensely bitter taste and significant biological activity. Its primary commercial value lies in its role as a key analytical reference standard for quality control in the herbal medicine and nutraceutical industries. This product is essential for manufacturers and research institutions involved in the development and standardization of bitter tonic formulations, phytopharmaceuticals, and botanical extracts.

Application

• Pharmaceutical Reference Standard: Used as a certified reference material (CRM) for the identification and quantification of amarogentin in herbal drug preparations and finished products via HPLC or LC-MS.
• Bitter Flavor Agent Research: Serves as a pure standard in the study and development of natural bittering agents for food, beverage, and digestive health formulations.
• Phytochemical & Pharmacological Research: Employed in academic and industrial R&D to investigate the anti-inflammatory, anti-diabetic, hepatoprotective, and anti-malarial properties attributed to this compound.
• Herbal Extract Standardization: Critical for the quality assurance of extracts derived from Swertia chirayita (Chiretta) and other Gentianaceae species, ensuring batch-to-batch consistency and potency.
• Dietary Supplement Analysis: Used by quality control laboratories to verify label claims and adulteration in bitter tonic and herbal supplement products.
• Biochemical Pathway Studies: Applied in research exploring the biosynthesis of secoiridoids in plants.

Basic Information

Product Name	Amarogentin
CAS No.	21018-84-8
Molecular Formula	C29H30O13
Molecular Weight	586.54 g/mol
Synonyms	Amarogentin; Amarogentine; (1S,4aS,5S,7S,7aS)-5-(β-D-Glucopyranosyloxy)-1,4a,5,7-tetrahydro-7-hydroxy-7-methyl-1,8-bis(3,4,5-trihydroxybenzoyl)oxy]cyclopenta[c]pyran-4-carboxylic acid methyl ester; Gentiopicrin (Note: often confused but distinct); Swertiamarin (related compound); Chiretta bitter principle; Swertia bitter glycoside
EINECS	Contact for details

Quality Control

Our Amarogentin is produced and handled under strict quality management protocols. Each batch is subjected to comprehensive analytical testing, including HPLC for purity verification and spectroscopic methods (IR, NMR, MS) for structural confirmation, to ensure it meets the high standards required for research and analytical applications. A detailed Certificate of Analysis (COA) specifying batch-specific results for identity, purity, and related substances is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent absorption of moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Purity (HPLC)	≥ 95.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals (as Pb)	≤ 20 ppm
Solubility	Soluble in methanol, DMSO; slightly soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.