Description

(S)-(+)-2-Phenylglycinol is a high-value chiral amino alcohol and a versatile building block in asymmetric synthesis. Its importance lies in its role as a key intermediate for the production of optically active pharmaceuticals and fine chemicals. This product is essential for research and manufacturing in the pharmaceutical, agrochemical, and specialty chemical industries, where precise stereochemistry is critical for biological activity and process efficiency.

Application

• Chiral Auxiliary and Ligand Precursor: Used in the synthesis of chiral catalysts and ligands for asymmetric hydrogenation and other enantioselective transformations.
• Pharmaceutical Intermediate: A critical building block for active pharmaceutical ingredients (APIs), particularly in the synthesis of β-blockers, antiviral agents, and other therapeutics.
• Agrochemical Synthesis: Employed in the production of enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Fine Chemical Production: Serves as a starting material for flavors, fragrances, and advanced materials requiring specific optical purity.
• Academic and R&D: A valuable reagent for methodological development in organic chemistry and medicinal chemistry research laboratories.

Basic Information

Product Name	(S)-(+)-2-Phenylglycinol
CAS No.	20989-17-7
Molecular Formula	C8H11NO
Molecular Weight	137.18 g/mol
Synonyms	(S)-(+)-2-Amino-2-phenylethanol; (S)-2-Phenyl-2-aminoethanol; (S)-2-Phenylglycinol; (S)-2-Hydroxy-1-phenylethylamine; (S)-α-(Aminomethyl)benzyl alcohol; L-2-Phenylglycinol; (S)-Phenylglycinol; (1S)-2-Amino-1-phenylethanol
EINECS	244-149-7

Quality Control

Our (S)-(+)-2-Phenylglycinol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity (enantiomeric excess) and chemical purity determination by HPLC, to ensure it meets the high standards required for pharmaceutical and fine chemical applications. A Certificate of Analysis (COA) detailing specific results for identity, assay, impurities, and optical rotation is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); containers must be kept tightly sealed to prevent absorption of atmospheric moisture, which can affect quality.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (HPLC)	≥ 99.0%
Melting Point	Contact for details
Specific Rotation	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.