Description

Trimethyl-[1,1,4,4,4-Pentakis(trimethylsilyl)but-2-ynyl]silane is a highly functionalized organosilicon compound featuring a unique alkyne core surrounded by multiple trimethylsilyl protecting groups. This complex molecular architecture makes it a valuable specialty reagent and building block for advanced synthetic chemistry, particularly in the development of novel silicon-containing materials and complex molecular scaffolds. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for constructing sophisticated molecular architectures.

Application

• Advanced Organic Synthesis: Serves as a key protected alkyne and silicon-containing building block for constructing complex molecules in pharmaceutical and agrochemical research.
• Material Science Precursor: Used in the development of novel silicon-based polymers, dendrimers, and hybrid organic-inorganic materials.
• Cross-Coupling Reactions: Acts as a substrate or reagent in Sonogashira, Hiyama, and other palladium-catalyzed coupling reactions to introduce silicon-protected alkynyl groups.
• Protecting Group Strategy: The multiple trimethylsilyl groups can be used for the selective protection and deprotection of alkynes in multi-step synthetic sequences.
• Ligand and Catalyst Development: Employed as a precursor for synthesizing specialized ligands or organometallic complexes for catalysis.
• Academic and Industrial R&D: A valuable tool for exploring new synthetic methodologies and reaction pathways in university and corporate research laboratories.

Basic Information

Product Name	Trimethyl-[1,1,4,4,4-Pentakis(trimethylsilyl)but-2-ynyl]silane
CAS No.	20932-80-3
Molecular Formula	C20H48Si6
Molecular Weight	457.1 g/mol
Synonyms	1,1,4,4,4-Pentakis(trimethylsilyl)-2-butynyltrimethylsilane; Tris(trimethylsilyl)propargyltris(trimethylsilyl)silane; (3,3,3-Tris(trimethylsilyl)-1-propynyl)tris(trimethylsilyl)silane; Silane, trimethyl[1,1,4,4,4-pentakis(trimethylsilyl)-2-butyn-1-yl]-; TMS-protected alkyne silane reagent
EINECS	Contact for details

Quality Control

Our production of Trimethyl-[1,1,4,4,4-Pentakis(trimethylsilyl)but-2-ynyl]silane adheres to stringent internal quality standards to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is characterized using advanced analytical techniques including NMR (¹H, ¹³C, ²⁹Si), GC-MS, and FT-IR to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all relevant specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, the container should be kept tightly sealed under an inert atmosphere (argon or nitrogen) when not in use to prevent degradation. Recommended long-term storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (NMR)	Conforms to structure
Purity (GC)	≥ 95%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.