Description

Saikosaponin D is a bioactive triterpenoid saponin primarily extracted from the roots of *Bupleurum* species, a key herb in traditional medicine. This high-purity reference standard is critical for pharmaceutical research and development, offering a reliable benchmark for quality control and biological activity studies. It is essential for manufacturers and research institutions in the pharmaceutical, nutraceutical, and academic sectors focused on anti-inflammatory, hepatoprotective, and antiviral applications.

Application

• Pharmaceutical Reference Standard: Serves as a primary chemical reference material (CRM) for the quality control and standardization of herbal extracts and finished pharmaceutical products.
• Biomedical Research: Used in in vitro and in vivo studies to investigate mechanisms of action related to anti-inflammatory, immunomodulatory, and antiviral activities.
• Nutraceutical Development: Incorporated into high-end dietary supplements targeting liver health and immune system support, where standardized bioactive content is required.
• Analytical Chemistry: Employed as an external standard in HPLC, LC-MS, and TLC methods for the quantitative and qualitative analysis of complex botanical matrices.
• Cosmeceutical Formulations: Explored for potential use in topical applications aimed at soothing skin irritation due to its anti-inflammatory properties.

Basic Information

Product Name	Saikosaponin D
CAS No.	20874-52-6
Molecular Formula	C42H68O13
Molecular Weight	780.98 g/mol
Synonyms	Saikosaponin D; Chikusetsusaponin IVa; SSd; (3β,4α,16β)-13,28-Epoxy-16,23-dihydroxyolean-11-en-3-yl O-6-deoxy-α-L-mannopyranosyl-(1→2)-O-β-D-glucopyranosyl-(1→3)-β-D-fucopyranoside
EINECS	Contact for details

Quality Control

Our Saikosaponin D is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, IR and MS for structural confirmation, and residual solvent analysis. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to ensure traceability and compliance with your research or production standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled in a low-humidity environment to maintain stability and potency.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥98.0%
Loss on Drying	≤2.0%
Residue on Ignition	≤0.5%
Heavy Metals	≤20 ppm
Residual Solvents	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.