Description

4-Bromoisatin is a versatile halogenated isatin derivative, a key heterocyclic building block in organic synthesis. Its value lies in its reactive bromine and carbonyl groups, enabling the construction of complex molecular frameworks. This intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries developing novel active compounds.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of kinase inhibitors, anti-cancer agents, and other bioactive molecules.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and plant growth regulators.
• Material Science: Serves as a building block for organic semiconductors, dyes, and functional polymers.
• Organic Synthesis: Employed in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) and as a scaffold for complex heterocycles.
• Research & Development: A valuable tool for medicinal chemists in structure-activity relationship (SAR) studies and library synthesis.

Basic Information

Item	Detail
Product Name	4-Bromoisatin
CAS No.	20780-72-7
Molecular Formula	C8H4BrNO2
Molecular Weight	226.03 g/mol
Synonyms	4-Bromo-1H-indole-2,3-dione; 4-Bromo-2,3-dioxoindoline; 4-Bromoindoline-2,3-dione; 4-Bromoisatin; 4-Bromooxindole; Isatin, 4-bromo-; 4-Bromo-1H-indole-2,3-dione
EINECS	Contact for details

Quality Control

Our 4-Bromoisatin is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy. Certificates of Analysis (COA) detailing all specifications are provided to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; ensure containers are sealed tightly after each use to minimize exposure to air and humidity.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	245 - 250 °C
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.