Description

1,2-Dithiolane-3-Carboxylicacid,(R)-(-)-(8Ci) is a chiral, sulfur-containing heterocyclic compound of significant interest in organic synthesis and pharmaceutical research. This molecule, also known as (R)-α-Lipoic acid, is a critical building block and a biologically active form of the essential cofactor. It is primarily sought after by research institutions and fine chemical manufacturers developing novel therapeutics, nutritional supplements, and advanced materials. The compound's unique dithiolane ring structure imparts redox-active properties, making it valuable for studying metabolic pathways and antioxidant mechanisms.

Application

• Pharmaceutical Intermediate: Serves as a key chiral precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for metabolic and neurological disorders.
• Nutraceutical & Dietary Supplement Production: Used in the manufacture of high-purity (R)-α-Lipoic acid, a potent antioxidant and essential metabolic cofactor.
• Biochemical Research: Employed as a standard or reagent in studies of mitochondrial function, oxidative stress, and redox signaling pathways.
• Asymmetric Synthesis: Utilized as a chiral auxiliary or ligand in catalytic processes to induce stereoselectivity in organic transformations.
• Cosmeceutical Formulations: Incorporated into advanced skincare products for its antioxidant and anti-aging properties.
• Veterinary Medicine: Applied in the development of supplements and treatments for animal health.

Basic Information

Product Name	1,2-Dithiolane-3-Carboxylicacid,(R)-(-)-(8Ci)
CAS No.	20752-39-0
Molecular Formula	C6H10O2S2
Molecular Weight	178.27 g/mol
Synonyms	(R)-α-Lipoic Acid; (R)-(+)-1,2-Dithiolane-3-pentanoic Acid; (R)-6,8-Thioctic Acid; (R)-5-(1,2-Dithiolan-3-yl)valeric Acid; (R)-1,2-Dithiolane-3-valeric Acid; (R)-6,8-Dithiooctanoic Acid; (R)-ALA; R-LA
EINECS	Contact for details

Quality Control

Our 1,2-Dithiolane-3-Carboxylicacid,(R)-(-)-(8Ci) is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis, to ensure it meets the stringent requirements for research and pharmaceutical applications. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting identity, purity, and specific impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is light-sensitive and should be handled under an inert atmosphere when appropriate to prevent oxidation.

Specification

Item	Specification
Appearance	Yellow to light yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% (R)-enantiomer
Melting Point	46 - 50 °C
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.