Description

7-Bromoquinoline-8-Thiol is a versatile sulfur-containing heterocyclic building block with a bromine substituent, offering dual reactive sites for advanced synthetic chemistry. This compound is valued for its role in constructing complex molecular architectures, particularly in the development of pharmaceuticals and functional materials. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries who require high-purity intermediates for drug discovery and specialty chemical synthesis.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, especially those targeting various enzyme systems.
• Agrochemical Research: Used in the development of novel pesticides and herbicides due to its bioactive quinoline-thiol structure.
• Ligand Synthesis: Serves as a starting material for creating complex chelating ligands in coordination chemistry and catalysis.
• Material Science: Employed in the research of organic semiconductors and conductive polymers.
• Chemical Biology Probes: Utilized for developing fluorescent probes or activity-based protein profiling reagents.
• Cross-Coupling Reactions: The bromine atom makes it a suitable substrate for palladium-catalyzed reactions like Suzuki or Buchwald-Hartwig amination.

Basic Information

Product Name	7-Bromoquinoline-8-Thiol
CAS No.	20738-25-4
Molecular Formula	C9H6BrNS
Molecular Weight	240.12 g/mol
Synonyms	8-Mercapto-7-bromoquinoline; 7-Bromo-8-mercaptoquinoline; 7-Bromoquinoline-8-thiol; Quinoline, 7-bromo-8-mercapto-; 8-Quinolinethiol, 7-bromo-; 7-Bromo-8-quinolinethiol
EINECS	Contact for details

Quality Control

Our 7-Bromoquinoline-8-Thiol is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and consistency. Certificates of Analysis (COA) detailing all specifications are available upon request, supporting compliance with research and cGMP standards where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C) under an inert atmosphere, such as nitrogen or argon, due to its sensitivity to oxidation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Light yellow to yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.