Description

Diethyl(4-Bromophenyl)Phosphonate is a versatile organophosphorus compound that serves as a critical synthetic intermediate in advanced chemical manufacturing. Its value lies in the reactive bromophenyl and phosphonate ester functional groups, enabling precise carbon-carbon and carbon-phosphorus bond formation. This high-purity building block is essential for researchers and production chemists in the pharmaceutical, agrochemical, and materials science industries developing novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of biologically active molecules, including kinase inhibitors and other therapeutic agents.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and plant growth regulators.
• Ligand and Catalyst Preparation: Serves as a starting material for synthesizing phosphonate-based ligands for metal catalysis and cross-coupling reactions.
• Material Science: Building block for flame retardants, plasticizers, and specialty polymers requiring brominated or phosphonated motifs.
• Organic Synthesis: Employed in Horner-Wadsworth-Emmons (HWE) olefination reactions to construct alkenes and in other carbon-carbon bond-forming processes.
• Research & Development: A valuable reagent for medicinal chemistry and process chemistry research in both academic and industrial settings.

Basic Information

Product Name	Diethyl(4-Bromophenyl)Phosphonate
CAS No.	20677-12-7
Molecular Formula	C10H14BrO3P
Molecular Weight	293.10 g/mol
Synonyms	Diethyl p-Bromophenylphosphonate; (4-Bromophenyl)phosphonic Acid Diethyl Ester; Diethyl (4-Bromophenyl)Phosphonate; Diethyl P-Bromobenzene Phosphonate; Phosphonic Acid, P-(4-Bromophenyl)-, Diethyl Ester; Diethyl 4-Bromobenzene Phosphonate; 20677-12-7; p-Bromophenylphosphonic Acid Diethyl Ester
EINECS	Contact for details

Quality Control

Our Diethyl(4-Bromophenyl)Phosphonate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to confirm identity and purity. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We support cGMP compliance for pharmaceutical applications and can tailor specifications to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases and incompatible materials. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.