Description

Tetrahydrofuran-2,2,5,5-D4 is a deuterated analog of tetrahydrofuran, where four hydrogen atoms are replaced by deuterium atoms. This isotopic labeling is critical for applications requiring non-interfering spectroscopic analysis and mechanistic studies. It is an essential reagent for researchers and industries focused on advanced materials, pharmaceutical development, and analytical chemistry, particularly in Nuclear Magnetic Resonance (NMR) spectroscopy.

Application

• As a deuterated solvent for high-resolution Nuclear Magnetic Resonance (NMR) spectroscopy in structural elucidation.
• As a chemical intermediate in the synthesis of deuterium-labeled pharmaceutical compounds for metabolic and pharmacokinetic studies.
• For use in organic light-emitting diode (OLED) and semiconductor research where isotopic purity is required.
• In polymer science as a solvent or monomer for studying polymerization mechanisms using deuterium tracing.
• As a specialty solvent in analytical chemistry and chromatography where proton interference must be minimized.
• For Fourier-transform infrared (FTIR) spectroscopy as a background solvent or for preparing deuterated samples.

Basic Information

Item	Details
Product Name	Tetrahydrofuran-2,2,5,5-D4
CAS No.	20665-63-8
Molecular Formula	C4D4O
Molecular Weight	76.13 g/mol
Synonyms	THF-d4; Deuterated Tetrahydrofuran; Tetrahydrofuran-d4; [2H4]-Tetrahydrofuran; Perdeuterotetrahydrofuran (partial); Oxolane-2,2,5,5-d4; 1,4-Epoxybutane-d4; Butylene oxide-d4
EINECS	Contact for details

Quality Control

Our Tetrahydrofuran-2,2,5,5-D4 is produced and tested to meet the stringent requirements for deuterated solvents. Each batch undergoes rigorous analysis to ensure high isotopic purity and chemical integrity. A comprehensive Certificate of Analysis (COA) detailing isotopic enrichment, assay, and impurity profiles is provided to guarantee consistency for your sensitive applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area away from heat sources and incompatible materials such as strong oxidizing agents. Due to its highly volatile nature, ensure containers are kept tightly sealed when not in use.

Specification

Item	Specification
Appearance	Clear, colorless liquid
Identification (IR)	Conforms
Deuterium Content (NMR)	≥ 99.0 atom % D
Assay (GC)	≥ 99.5%
Water Content (KF)	≤ 0.05%
Residue after Evaporation	≤ 0.01%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.