Description

[2R,6R,(-)]-1,2,3,4,5,6-Hexahydro-3,11-Dimethyl-6-Propyl-2α,6α-Methano-3-Benzazocine-8-Ol CAS NO 20662-42-4 is a high-purity, stereochemically defined benzazocine derivative, a key intermediate in advanced pharmaceutical synthesis. This compound matters for its role as a critical chiral building block in the development of potent analgesic and neuropharmacological agents, enabling precise control over biological activity. It is primarily needed by research institutions and pharmaceutical manufacturers engaged in the development of novel central nervous system (CNS) therapeutics and for analytical reference standards.

Application

• Pharmaceutical Intermediate: A crucial chiral precursor in the synthesis of opioid receptor-targeting drugs and other neuroactive compounds.
• Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and the discovery of new analgesic pathways.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Chemical Synthesis: Employed as a specialized building block for constructing complex polycyclic molecular architectures in organic chemistry.
• Biochemical Research: Utilized in vitro studies to investigate ligand-receptor interactions within the opioid receptor family.

Basic Information

Product Name	[2R,6R,(-)]-1,2,3,4,5,6-Hexahydro-3,11-Dimethyl-6-Propyl-2α,6α-Methano-3-Benzazocine-8-Ol
CAS No.	20662-42-4
Molecular Formula	C₁₉H₂₉NO
Molecular Weight	287.44 g/mol
Synonyms	(-)-Pentazocine; (2R,6R,11R)-1,2,3,4,5,6-Hexahydro-6,11-dimethyl-3-(3-methyl-2-butenyl)-2,6-methano-3-benzazocin-8-ol; Levophenacylmorphan; Win 20228; 2'R,6'R,11'R-(-)-Pentazocine; 2'R,6'R,11'R-(-)-1,2,3,4,5,6-Hexahydro-cis-6,11-dimethyl-3-(3-methyl-2-butenyl)-2,6-methano-3-benzazocin-8-ol; (-)-cis-Pentazocine
EINECS	Contact for details

Quality Control

Our [2R,6R,(-)]-1,2,3,4,5,6-Hexahydro-3,11-Dimethyl-6-Propyl-2α,6α-Methano-3-Benzazocine-8-Ol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical R&D and synthesis. Certificates of Analysis (COA) detailing identity, purity, and chiral excess are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; ensure containers are sealed under an inert atmosphere if necessary after opening to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.