Description

Dimethyl N,n-Diethyl Phosphoramidite is a key organophosphorus reagent widely used in chemical synthesis. This compound is valued for its role as a versatile intermediate in the preparation of complex phosphorous-containing molecules, including ligands, catalysts, and biologically active compounds. It is primarily sought by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for advanced synthesis and process development.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of nucleotide analogs, prodrugs, and other active pharmaceutical ingredients (APIs).
• Ligand Synthesis: Used to prepare phosphine and phosphite ligands for homogeneous catalysis and transition metal complexes.
• Agrochemical Production: Serves as an intermediate in the manufacture of pesticides, herbicides, and plant growth regulators.
• Chemical Research: Employed in academic and industrial R&D for developing new organophosphorus chemistry and methodologies.
• Polymer Chemistry: Acts as a monomer or modifier in the synthesis of specialty polymers and flame retardants.
• Material Science: Used in surface modification and the creation of advanced functional materials.

Basic Information

Product Name	Dimethyl N,n-Diethyl Phosphoramidite
CAS No.	20621-25-4
Molecular Formula	C6H16NO2P
Molecular Weight	165.17 g/mol
Synonyms	Diethylamino-dimethylphosphonite; (Diethylamino)dimethoxyphosphine; Phosphoramidous acid, N,N-diethyl-, dimethyl ester; N,N-Diethylphosphoramidous acid dimethyl ester; Dimethoxy(diethylamino)phosphine; DMDP; Diethylaminodimethoxyphosphine
EINECS	Contact for details

Quality Control

Our Dimethyl N,n-Diethyl Phosphoramidite is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including chromatographic purity analysis and identity confirmation, to ensure it meets the high standards required for sensitive synthetic applications. A Certificate of Analysis (COA) detailing specific results is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture ingress and decomposition.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.