Description

Cyclohexanol, 2-(Trimethylsilyl)-, cis- CAS NO 20584-43-4 is a specialized organosilicon derivative of cyclohexanol, valued for its unique steric and electronic properties imparted by the trimethylsilyl group. This compound serves as a versatile synthetic intermediate and protecting group reagent in advanced organic synthesis, particularly for fine chemical and pharmaceutical manufacturing. Key industries that utilize this chemical include pharmaceutical R&D, agrochemical production, and advanced material science, where precise molecular modification is required.

Application

• Pharmaceutical Intermediate: Used in the synthesis of complex drug molecules, particularly where steric protection of hydroxyl groups is necessary.
• Agrochemical Synthesis: Serves as a key building block in the production of advanced pesticides and herbicides.
• Organosilicon Chemistry: Acts as a precursor or reagent in the development of silicone-based polymers and functional materials.
• Asymmetric Synthesis: Employed in chiral synthesis due to the defined stereochemistry of the cis-configured cyclohexanol ring.
• Protecting Group Chemistry: The trimethylsilyl (TMS) group is used to temporarily protect alcohol functionalities during multi-step synthetic sequences.
• Ligand and Catalyst Development: Utilized in the research and preparation of novel ligands for catalytic systems.

Basic Information

Product Name	Cyclohexanol, 2-(Trimethylsilyl)-, cis-
CAS No.	20584-43-4
Molecular Formula	C9H20OSi
Molecular Weight	172.34 g/mol
Synonyms	cis-2-(Trimethylsilyl)cyclohexanol; (1s,2s)-2-(Trimethylsilyl)cyclohexanol; 2-(Trimethylsilyl)cyclohexanol, cis-; Cyclohexanol, 2-(trimethylsilyl)-, (1R,2R)-rel-; TMS-Cyclohexanol; 2-TMS-cyclohexanol; 2-Trimethylsilylcyclohexanol
EINECS	Contact for details

Quality Control

Our Cyclohexanol, 2-(Trimethylsilyl)-, cis- is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical parameters are available upon request, providing full traceability and compliance assurance for your quality systems.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 97.0%
Purity (HPLC)	≥ 96.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.