Description

1-Benzothiophen-5-Amine is a versatile heterocyclic aromatic amine building block of significant importance in advanced organic synthesis. Its core value lies in its role as a key intermediate for constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and functional materials. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries seeking to develop novel compounds with specific electronic or biological properties.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging the benzothiophene scaffold for bioactivity.
• Material Science & Organic Electronics: Serves as a building block for organic semiconductors, conductive polymers, and light-emitting materials due to its electron-rich thiophene core.
• Dye & Pigment Manufacturing: Employed in the synthesis of specialized dyes and pigments where the amine group allows for further functionalization and color tuning.
• Research & Development: A valuable reagent in academic and industrial R&D for exploring new chemical reactions and creating libraries of novel heterocyclic compounds.
• Ligand Synthesis for Catalysis: Used to prepare nitrogen-containing ligands for transition metal catalysts used in asymmetric synthesis and cross-coupling reactions.

Basic Information

Product Name	1-Benzothiophen-5-Amine
CAS No.	20532-28-9
Molecular Formula	C8H7NS
Molecular Weight	149.21 g/mol
Synonyms	5-Aminobenzothiophene; Benzo[b]thiophen-5-amine; 1-Benzothiophene-5-amine; 5-Amino-1-benzothiophene; 5-Benzothienylamine; 5-Aminobenzo[b]thiophene; 1-Benzothien-5-ylamine
EINECS	Contact for details

Quality Control

Our 1-Benzothiophen-5-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing identity, purity, and impurity profiles. Our quality commitment ensures the material meets the stringent requirements for research and cGMP-grade pharmaceutical intermediate applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber-colored or stored in light-resistant secondary packaging.

Specification

Item	Specification
Appearance	Light yellow to brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.