Description

Naphthalene-1-13C CAS NO 20526-83-4 is a stable isotope-labeled derivative of naphthalene, where the carbon atom at the 1-position is the carbon-13 (13C) isotope. This compound is essential as an internal standard and tracer in advanced analytical chemistry, enabling precise quantification and metabolic pathway elucidation. It is primarily utilized by research institutions, pharmaceutical developers, and analytical laboratories engaged in mass spectrometry, NMR spectroscopy, and environmental fate studies.

Application

• Internal Standard for Quantitative Analysis: Used in Gas Chromatography-Mass Spectrometry (GC-MS) and Liquid Chromatography-Mass Spectrometry (LC-MS) for the accurate measurement of naphthalene and related polycyclic aromatic hydrocarbons (PAHs) in complex matrices.
• Metabolic Tracing Studies: Serves as a crucial tracer in pharmaceutical and biochemical research to investigate the metabolic pathways and degradation products of naphthalene in biological systems.
• Environmental Science Research: Employed in fate and transport studies to track the environmental breakdown, bioavailability, and remediation of PAH contaminants.
• NMR Spectroscopy Reference: Provides a distinct 13C NMR signal for chemical shift referencing and structural analysis in nuclear magnetic resonance experiments.
• Isotope Dilution Mass Spectrometry (IDMS): A key component in high-precision IDMS methods, which are considered a gold standard for definitive analytical measurements.
• Pharmaceutical Impurity Profiling: Aids in the identification and quantification of naphthalene-related impurities or degradation products in active pharmaceutical ingredients (APIs) and drug products.

Basic Information

Product Name	Naphthalene-1-13C
CAS No.	20526-83-4
Molecular Formula	C913CH8 or C10H8 (with 13C at position 1)
Molecular Weight	129.18 g/mol (approx.)
Synonyms	1-13C-Naphthalene; [1-13C]Naphthalene; Naphthalene-1-13C; Naphthalene (1-13C); Carbon-13 Labeled Naphthalene; Isotopic Naphthalene; 13C1-Naphthalene; NSC 76545 (labeled form)
EINECS	Contact for details

Quality Control

Our Naphthalene-1-13C is produced and handled under strict quality protocols to ensure isotopic and chemical purity for sensitive research applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing key parameters such as isotopic enrichment (atom % 13C), chemical purity (by GC or HPLC), and identity confirmation. We adhere to relevant industry standards for stable isotope-labeled compounds to ensure reliable and reproducible performance in your analytical methods.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated area. Due to its highly volatile nature, ensure containers are securely sealed when not in use to prevent sublimation and potential cross-contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline solid
Identification (IR)	Conforms to structure
Isotopic Enrichment (atom % 13C)	≥ 99%
Chemical Purity (GC/HPLC)	≥ 98%
Melting Point	80 - 82 °C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.