Description

1-[2-(Triethylsilyloxy)Ethyl]Piperidine is a specialized organosilicon-protected amino alcohol derivative, serving as a versatile building block and intermediate in advanced organic synthesis. Its core value lies in its dual functionality, where the piperidine ring acts as a base or directing group, and the triethylsilyl (TES) protecting group offers selective deprotection strategies. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries developing novel active ingredients, particularly where controlled introduction of basic nitrogen functionalities is required.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of complex drug candidates, especially those containing piperidine or morpholine-like pharmacophores.
• Agrochemical Synthesis: Used in the development of novel pesticides and herbicides where its protected amino alcohol structure can be incorporated into active molecules.
• Ligand and Catalyst Precursor: Serves as a starting material for the preparation of chiral ligands or organocatalysts used in asymmetric synthesis.
• Organic Synthesis Reagent: Employed in multi-step syntheses as a protected form of 2-(piperidin-1-yl)ethanol, allowing for selective reactions at other sites on the molecule.
• Material Science Research: Potential monomer or modifier in the development of specialty polymers and functionalized surfaces.

Basic Information

Product Name	1-[2-(Triethylsilyloxy)Ethyl]Piperidine
CAS No.	20467-05-4
Molecular Formula	C13H29NOSi
Molecular Weight	243.46 g/mol
Synonyms	2-(Triethylsilyloxy)-1-(piperidin-1-yl)ethane; 1-(2-((Triethylsilyl)oxy)ethyl)piperidine; N-(2-(Triethylsilyloxy)ethyl)piperidine; 2-(Piperidin-1-yl)ethyl triethylsilyl ether; TES-protected 2-piperidinoethanol; 1-(2-Hydroxyethyl)piperidine triethylsilyl ether; 20467-05-4; Piperidine, 1-[2-[(triethylsilyl)oxy]ethyl]-
EINECS	Contact for details

Quality Control

Our 1-[2-(Triethylsilyloxy)Ethyl]Piperidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chromatographic purity assays and identity confirmation, to ensure it meets the high standards required for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation. Keep away from strong bases and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.