Description

Isometamidium Chloride CAS NO 20438-03-3 is a vital trypanocidal agent belonging to the phenanthridine class of compounds. It is a critical active pharmaceutical ingredient (API) used in veterinary medicine to combat parasitic infections. This compound is essential for manufacturers of veterinary pharmaceuticals and research institutions focused on animal health. Its efficacy against specific protozoan parasites makes it a cornerstone in the treatment and prevention of significant livestock diseases.

Application

• Veterinary Pharmaceutical Formulations: Primary use as the active ingredient in injectable solutions for the treatment of trypanosomiasis in animals.
• Livestock Health Management: Prophylactic and therapeutic control of diseases like Nagana in cattle and Surra in camels and horses, caused by *Trypanosoma* species.
• Veterinary Parasiticide Production: Serves as a key raw material for manufacturers producing anti-parasitic drugs for large and small animals.
• Research & Development: Used in biochemical and pharmacological studies to understand trypanocide mechanisms of action and resistance.
• Reference Standard: Employed as a high-purity analytical standard in quality control laboratories for drug testing and method validation.
• Animal Disease Control Programs: Integral to large-scale veterinary public health initiatives in regions endemic for animal trypanosomiasis.

Basic Information

Product Name	Isometamidium Chloride
CAS No.	20438-03-3
Molecular Formula	C₂₂H₂₃ClN₆O
Molecular Weight	422.91 g/mol
Synonyms	Isometamidium Chloride; Isometamidium Chloride Hemihydrate; 8-[(m-Amidinophenyl)azo]-7-amino-1,2,3,4-tetrahydro-2-methyl-6-phenanthridinamine Chloride; Samorin; Trypamidium; Homidium Chloride analogue; CL 38755; NSC 32917
EINECS	Contact for details

Quality Control

Our Isometamidium Chloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and potency meet stringent specifications. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting results for key parameters including assay, related substances, and residual solvents. We adhere to cGMP principles suitable for veterinary API production.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The product is light-sensitive (store away from light) and hygroscopic (moisture-sensitive). Keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	Dark red to brownish-red crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	NMT 5.0%
Related Substances (HPLC)	Total impurities: NMT 2.0% Any individual impurity: NMT 1.0%
Residue on Ignition	NMT 0.1%
Heavy Metals	NMT 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.