Description

2-(Trimethylacetyl)Thiophene is a specialized organic compound featuring a thiophene ring substituted with a trimethylacetyl (pivaloyl) group, serving as a versatile building block in advanced chemical synthesis. Its unique structure makes it a valuable intermediate for creating complex molecules with tailored properties for high-performance applications. This compound is essential for research and development chemists and process engineers in the pharmaceutical, agrochemical, and material science industries seeking to develop new active ingredients or functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and production of novel active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders or other therapeutic areas.
• Agrochemical Synthesis: Used in the development of next-generation pesticides, herbicides, and fungicides, where the thiophene moiety can contribute to biological activity.
• Material Science Precursor: Acts as a monomer or functionalization agent in the synthesis of conductive polymers, organic semiconductors, and other advanced electronic materials.
• Ligand and Catalyst Development: Employed in organometallic chemistry to create novel ligands for catalysis, enabling more efficient and selective chemical transformations.
• Fine Chemical and Flavor/Fragrance Intermediate: Utilized in the synthesis of complex molecules for specialty chemicals, flavors, and fragrances.
• Academic and Industrial R&D: Serves as a critical research chemical for method development and exploring new reaction pathways in organic chemistry.

Basic Information

Product Name	2-(Trimethylacetyl)Thiophene
CAS No.	20409-48-7
Molecular Formula	C9H12OS
Molecular Weight	168.26 g/mol
Synonyms	2-Pivaloylthiophene; Thiophen-2-yl trimethyl ketone; 2-Trimethylacetylthiophene; 2-(2,2-Dimethylpropanoyl)thiophene; Pivaloylthiophene; 2-Thienyl pivalyl ketone; α,α-Dimethyl-2-thiopheneacetyl ketone; 2-(2,2-Dimethylpropionyl)thiophene
EINECS	Contact for details

Quality Control

Our 2-(Trimethylacetyl)Thiophene is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as identity, assay, and impurity profiles. Our quality commitment aligns with cGMP principles where applicable, supporting its use in regulated research and development environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and bases. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC/GC)	≥97.0%
Melting Point	Contact for details
Related Substances (HPLC)	Total impurities ≤3.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.