Description

(Z)-1-Chloro-1-Buten-3-Yne is a highly reactive halogenated alkyne building block of significant interest in advanced organic synthesis. Its unique structure, featuring both a chloro and an alkyne group, makes it a versatile precursor for constructing complex molecular architectures. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the preparation of complex heterocycles and bioactive molecules in drug discovery and development.
• Agrochemical Synthesis: Used in the production of advanced pesticides, herbicides, and plant growth regulators.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of specialty polymers and advanced materials.
• Organic Synthesis Building Block: Employed in Sonogashira coupling, cycloaddition, and other cross-coupling reactions to introduce functionalized acetylene units.
• Ligand and Catalyst Development: Useful for synthesizing novel ligands and organometallic complexes for catalytic applications.

Basic Information

Product Name	(Z)-1-Chloro-1-Buten-3-Yne
CAS No.	20374-90-7
Molecular Formula	C4H3Cl
Molecular Weight	86.52 g/mol
Synonyms	1-Chloro-1-buten-3-yne (Z-isomer); (Z)-1-Chloro-1-buten-3-yne; (Z)-1-Chloro-1-buten-3-yne; 1-Chloro-1-buten-3-yne; 1-Chloro-1-butyne-3-ene; 1-Chloro-1-buten-3-yne, (Z)-; 1-Chloro-1-buten-3-yne, (cis)-; 1-Chloro-1-buten-3-yne, cis-
EINECS	Contact for details

Quality Control

Our (Z)-1-Chloro-1-Buten-3-Yne is produced under stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including GC, HPLC, and NMR, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications. We support cGMP and ISO 9001 standards for research and development materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated place, away from heat, sparks, and open flame. Due to its highly volatile nature, containers should be kept tightly sealed and under an inert atmosphere (e.g., nitrogen or argon) when not in use to prevent degradation and maintain purity. Recommended storage temperature is 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.