Description

2-Methyl-1,2,3,4-Tetrahydro-Isoquinoline-3-Carboxylic Acid Hydrochloride is a high-purity, synthetically derived organic compound that serves as a critical chiral building block and intermediate in advanced chemical synthesis. Its value lies in the unique structural framework it provides, enabling the development of complex molecules with specific stereochemistry. This product is essential for research and production in the pharmaceutical industry, particularly for medicinal chemists developing novel active pharmaceutical ingredients (APIs) and fine chemical manufacturers.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and synthesis of potential drug candidates, especially for central nervous system (CNS) targets and other therapeutic areas.
• Fine Chemical Synthesis: Used as a versatile building block for constructing complex heterocyclic compounds and natural product analogs in laboratory and pilot-scale production.
• Agrochemical Research: Employed in the development of novel pesticides and herbicides where the tetrahydroisoquinoline scaffold is biologically active.
• Academic & R&D: Serves as a valuable reagent for methodological studies in organic chemistry, asymmetric synthesis, and catalysis research.
• Chemical Reference Standard: Supplied as a high-purity standard for analytical method development, quality control, and regulatory submissions.

Basic Information

Item	Detail
Product Name	2-Methyl-1,2,3,4-Tetrahydro-Isoquinoline-3-Carboxylic Acid Hydrochloride
CAS No.	20335-68-6
Molecular Formula	C11H14ClNO2
Molecular Weight	227.69 g/mol
Synonyms	2-Methyl-1,2,3,4-tetrahydro-3-isoquinolinecarboxylic acid hydrochloride; (3S)-2-Methyl-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid hydrochloride (if applicable to stereoisomer); MTIQ-CA HCl; 2-Methyl-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid HCl; 3-Carboxy-2-methyl-1,2,3,4-tetrahydroisoquinoline hydrochloride
EINECS	Contact for details

Quality Control

Every batch of 2-Methyl-1,2,3,4-Tetrahydro-Isoquinoline-3-Carboxylic Acid Hydrochloride is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and chiral purity analysis, to ensure compliance with exacting standards for research and pharmaceutical applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under anhydrous conditions to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (if applicable)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.