Description

2-(D-α-Methylphenethylamino)Ethanethiol is a specialized chiral thiol derivative of pharmaceutical significance. This compound serves as a critical intermediate in the synthesis of optically active molecules, offering a valuable handle for introducing sulfur-containing functional groups. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs) and fine chemicals. The precise stereochemistry and functional group combination make it a key building block for advanced synthetic applications.

Application

• Pharmaceutical Intermediate: Key chiral building block in the synthesis of novel drug candidates, particularly those targeting neurological and cardiovascular pathways.
• Asymmetric Synthesis: Employed as a ligand precursor or chiral auxiliary in catalytic asymmetric reactions to induce stereoselectivity.
• Peptidomimetics Research: Used in the design and construction of peptide analogs and mimetics where the thiol and amine functionalities are crucial.
• Chemical Biology Probes: Serves as a starting material for creating molecular probes to study enzyme mechanisms or protein interactions.
• Fine Chemical Production: Integral in multi-step syntheses of complex, high-value specialty chemicals for agrochemical and material science applications.

Basic Information

Product Name	2-(D-α-Methylphenethylamino)Ethanethiol
CAS No.	20315-07-5
Molecular Formula	C11H17NS
Molecular Weight	195.32 g/mol
Synonyms	2-[(1R)-1-Methyl-2-phenylethylamino]ethanethiol; (R)-2-(1-Methyl-2-phenylethylamino)ethanethiol; D-2-(α-Methylphenethylamino)ethanethiol; (R)-α-Methylphenethylaminoethanethiol; 2-[(R)-α-Methylbenzylamino]ethanethiol; NSC 334365; 2-((R)-1-Phenylethylamino)ethanethiol (common misnomer)
EINECS	Contact for details

Quality Control

Our 2-(D-α-Methylphenethylamino)Ethanethiol is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity assessment by HPLC, to ensure identity, potency, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) for every shipment, confirming compliance with customer specifications and relevant industry standards for research and pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere to prevent oxidation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (HPLC)	≥ 98.0% ee (D-isomer)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.