Description

N,n-Dimethylacetamide-2,2,2-D3 CAS NO 20255-66-7 is a deuterated analog of the versatile polar aprotic solvent N,N-Dimethylacetamide (DMAc), where three hydrogen atoms on the acetyl methyl group are replaced with deuterium. This isotopic labeling makes it an indispensable tool in advanced research and analytical chemistry, particularly for Nuclear Magnetic Resonance (NMR) spectroscopy and reaction mechanism studies. It is primarily sought after by pharmaceutical R&D laboratories, academic research institutions, and specialty chemical manufacturers engaged in deuterium labeling, solvent effect studies, and as a non-exchangeable solvent for sensitive reactions.

Application

• NMR Spectroscopy Solvent: Used as a deuterated solvent for proton NMR to provide a lock signal and avoid interference from solvent protons, crucial for structural elucidation.
• Mechanistic Studies & Kinetic Isotope Effects (KIE): Employed to investigate reaction pathways and mechanisms by studying the effects of deuterium substitution on reaction rates.
• Deuterium Labeling Reagent: Serves as a source of deuterium atoms in synthetic chemistry for the preparation of labeled target molecules in pharmaceutical and material science research.
• Polymer & Fiber Industry Research: Used in R&D for processes involving polyacrylonitrile or polyimide polymers where solvent isotope effects are studied.
• Analytical Chemistry Standard: Acts as an internal standard or reference material in mass spectrometry and other analytical techniques.
• Electrolyte Additive Research: Investigated in advanced battery research for lithium-ion or other energy storage systems where solvent properties are critical.

Basic Information

Product Name	N,n-Dimethylacetamide-2,2,2-D3
CAS No.	20255-66-7
Molecular Formula	C4H7D3NO
Molecular Weight	90.14 g/mol
Synonyms	N,N-Dimethylacetamide-d3; DMAc-d3; Acetamide-d3, N,N-dimethyl-; Deuterated N,N-Dimethylacetamide; (Trideuterioacetyl)dimethylamine; Dimethylacetamide-2,2,2-d3; N,N-Dimethyl-d3-acetamide; DMAC-d3
EINECS	Contact for details

Quality Control

Our N,n-Dimethylacetamide-2,2,2-D3 is produced and handled under strict quality protocols to ensure high isotopic purity and chemical integrity, meeting the exacting standards of research applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing key parameters such as isotopic purity (D atom %), chemical purity by GC and NMR, and water content. We support compliance with relevant research and development guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, containers should be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	Colorless clear liquid
Identification (IR)	Conforms
Isotopic Purity (D atom %)	≥ 99.0%
Chemical Purity (GC)	≥ 99.5%
Water Content (KF)	≤ 0.1%
NMR Purity (1H NMR)	Conforms

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.